NOW:53209:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
28°
H 28° L 12°
Clear | 0MPH

Brain Irradiation in Lung Cancer

June 4, 2009

Prophylactic Cranial Irradiation PreventsEarly Lung Cancer Metastases to the Brain

 

A national Radiation Therapy Oncology Group (RTOG) study led by a Medical College of Wisconsin Cancer Center physician at Froedtert Hospital in Milwaukee has found that a course of radiation therapy to the brain after treatment for locally advanced non-small cell lung cancer reduced the risk of metastases to the brain within the first year after treatment. The study was presented at the American Society of Clinical Oncology annual meeting in Orlando, June 1.

“With improved treatments for non-small cell lung cancer, patients are living longer and we are seeing more brain metastases,” says study author Elizabeth Gore, M.D. “This study compared the efficacy of prophylactic (preventive) cranial irradiation (PCI) vs. observation in these patients, and found that those not receiving cranial irradiation were two and one-half times more likely to develop brain metastasis than those who did.”

The study analyzed 356 patients. While the results did not show a statistically significant difference in survival between the two groups, it did show that PCI significantly decreased the incidence of brain metastases during the first year post-treatment. Dr. Gore anticipates that additional study of the impact of PCI --on neuro-psychological function and quality of life in these patients-- will help determine if use of PCI should become standard care.

Dr. Gore is associate professor of radiation oncology at the Medical College.

Co investigators included K. Bae, of the Radiation Therapy Oncology Group, Philadelphia, PA; Stuart Wong, M.D. of the Medical College of Wisconsin; J. Bonner of the University of Alabama at Birmingham; A. Sun, of the Princess Margaret Hospital, University Health Network, University of Toronto; S. Schild of the Mayo Clinic Arizona in Scottsdale; L. E. Gaspar of the University of Colorado Cancer Center in Aurora; J. Bogart of SUNY Health Science Center at Syracuse, NY; M. Werner-Wasik of Thomas Jefferson University Hospital in Philadelphia, and H. Choy, University of Texas Southwestern Medical Center in Dallas.

RTOG, an NCI-funded national clinical trials group, is a clinical research component of the American College of Radiology (ACR). Through the NCI Clinical Trials Support Unit this study was open to members of the Eastern Cooperative Oncology Group the National Cancer Institute of Canada the North Central Cancer Treatment Group, the Southwest Oncology Group, and the Cancer & Leukemia Group B.

The research was funded by Grants from the National Cancer Institute.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Shorewood girls basketball team beats Bay for regional title, 52-40 2/28

» 'Project Runway' star, fiancé mesh styles and make small Shorewood apartment work 2/26

» Construction begins on Shorewood Metro Market project 2/24

» Shorewood school superintendent is a finalist for West Allis-West Milwaukee job 2/23

» West Allis superintendent finalists hail from Shorewood, Greendale, MPS 2/23

» Wrong-way drunken driver arrested on I-43 2/23

» Germantown boys basketball team clinches outright NSC title 2/20

» Germantown girls basketball team wins 2nd outright North Shore crown 2/20

» Blood drive to be held in Brown Deer Monday 2/19

» North Shore schools proactive against potential measles outbreak 2/18

» One candidate eliminated in Fox Point Village Board primary 2/17

» Shaw, Kennedy will face off in Glendale mayoral race 2/17

» Cade, Cain advance in Shorewood School Board primary 2/17

» New Bayshore Applebee's will open Wednesday 2/17

» Shorewood teacher named Wisconsin VFW Middle School Teacher of the Year 2/16

» Shorewood girls basketball team stifles Brown Deer, 48-22 2/13

» Germantown girls basketball team clinches share of second NSC crown 2/12

» Fox Point-Bayside hosts referendum information sessions 2/12

» Brown Deer boys get defensive in beating Homestead, 65-55. 2/11

» Children's Hospital of Wisconsin plans new Mequon clinic 2/11

» My Community Now and Lake Country Now websites switch to Viafoura commenting 2/9

» Shorewood woman dies after jumping off Hoan Bridge 2/9

» Whitefish Bay girls overpower Nicolet on senior night, 56-34 2/7

» Cedarburg girls beat Homestead in battle for second in NSC, 53-42 2/6

» Standoff on Estabrook dam could come to head Thursday 2/4

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement


Local Business Directory

CONNECT